U.S. Secretary of State Antony Blinken on Tuesday said Israel has not apprised the U.S. of any specific date for the start of a major offensive into the southern Gaza city of Rafah, but added that American and Israeli officials remained in contact to try to ensure that “any kind of major military operation doesn’t do real harm to civilians.”

Blinken spoke a day after Israeli Prime Minister Netanyahu vowed that a date has been set to invade Rafah. The United States, Israel’s closest ally, says a ground operation into Rafah would be a mistake and has demanded to see a credible plan to protect civilians.

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Rafah is filled with around 1.4 million Palestinians, most of whom are displaced from other parts of the Gaza Strip. Israel’s war against the militant group Hamas has pushed Gaza into a humanitarian crisis, leaving more than 1 million people on the brink of starvation.

International efforts to broker a cease-fire between Israel and Hamas are taking place in Cairo this week.

Israel’s bombardment and ground offensives in Gaza over the past six months have killed at least 33,360 Palestinians and wounded 74,993, Gaza’s Health Ministry said Tuesday. The ministry doesn’t differentiate between civilians and combatants in its tally, but says women and children make up two-thirds of the dead.

The war began Oct. 7 when Hamas-led militants stormed into southern Israel, killing some 1,200 people, mostly civilians, and taking around 250 people hostage.