The flight left Dhaka at 12:09pm and is scheduled to bring back some stranded Bangladeshis from London on Monday morning.
More than 130 Bangladeshi students, who were stranded in the UK since the suspension of international flights between Dhaka and London in the wake of the coronavirus pandemic, will return home by the flight, according to Bangladesh High Commission in UK.
Earlier, 58 Bangladesh-origin British citizens arrived in Dhaka from Sylhet on Sunday morning on a special flight of Novoair Airline.
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Later, they joined others and left for the UK at noon.
Over 1,800 British nationals have so far left Bangladesh for the UK by nine chartered flights between April 21 and May 7, according to British High Commission in Dhaka.
The UK government committed up to £75 million to help thousands of British people return home.
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Bangladesh has so far brought home stranded Bangladeshis from India, Australia, Thailand, Singapore and Myanmar.