University of Cambridge
Scientists find possible chemical signs of life on a faraway planet
Astronomers have found possible chemical signs of life on a distant planet outside our solar system, though they caution more work is needed to confirm their findings.
The research, led by scientists at the University of Cambridge, detected evidence of compounds in the exoplanet's atmosphere that on Earth are only produced by living organisms and contended it's the strongest potential signal yet of life.
Independent scientists described the findings as interesting, but not nearly enough to show the existence of life on another planet.
“It is the strongest sign to date of any possibility of biological activity outside the solar system," Cambridge astrophysicist Nikku Madhusudhan said during a livestream on Thursday.
By analyzing data from NASA and the European Space Agency's Webb Space Telescope, the researchers found evidence of dimethyl sulfide and dimethyl disulfide in the atmosphere of the planet known as K2-18b. The planet is 124 light-years away; one light-year is equivalent to nearly 6 trillion miles.
On Earth, those two compounds are produced primarily by microbial life, such as marine phytoplankton.
Telescope finds promising hints of life on distant planet
The planet is more than double Earth’s size and more than 8 times more massive. It's in the so-called habitable zone of its star. The study appeared in the journal Astrophysical Journal Letters.
Madhusudhan stressed that further research is needed to rule out any errors or the possibility of other processes, besides living organisms, that could produce the compounds.
David Clements, an astrophysicist at Imperial College London, said atmospheres on other planets are complex and difficult to understand, especially with the limited information available from a planet so far away.
“This is really interesting stuff and, while it does not yet represent a clear detection of dimethyl sulfide and dimethyl disulfide, it is a step in the right direction,” he said in comments released by the Science Media Center in London.
More than 5,500 planets orbiting other stars have been confirmed so far. Thousands more are in the running out of the billions out there in our Milky Way galaxy alone.
Launched in 2021, Webb is the biggest and most powerful observatory ever sent into space.
1 month ago
Groundbreaking: Scientists create first human synthetic model embryos
In a groundbreaking development, scientists have generated synthetic human embryos using stem cells that sidestep the need for eggs or sperm, The Guardian reports.
These model embryos, which mirror those in the earliest stages of human development, may offer a significant insight into the effects of genetic anomalies and the biological factors that contribute to recurrent miscarriage, according to scientists.
Since lab-grown entities are illegal in the UK and most other nations, the development also poses significant ethical and legal concerns.
The structures contain cells that would ordinarily develop into the placenta, yolk sac, and embryo itself but lack a beating heart and the beginnings of a brain, reports the Guardian.
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Prof Magdalena Żernicka-Goetz, of the University of Cambridge and the California Institute of Technology, described the work in a plenary address on Wednesday at the International Society for Stem Cell Research’s annual meeting in Boston.
“We can create human embryo-like models by the reprogramming of [embryonic stem] cells,” she told the meeting.
According to The Guardian, the use of synthetic embryos in clinical trials is not anticipated to happen anytime soon. It is currently unknown if these structures have the ability to continue maturing past the initial stages of development, making their implantation into a patient's womb illegal.
The goal of the research is to help scientists better comprehend the so-called "black box" period of development, which lasts for only 14 days in accordance with regulatory restrictions. They then pick up the development's course at a far later stage by examining donated embryos and pregnancy scans.
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“The idea is that if you really model normal human embryonic development using stem cells, you can gain an awful lot of information about how we begin development, what can go wrong, without having to use early embryos for research,” Robin Lovell-Badge, the head of stem cell biology and developmental genetics at the Francis Crick Institute in London, told The Guardian.
Previously, Żernicka-Goetz’s team and a rival group at the Weizmann Institute in Israel showed that stem cells from mice could be encouraged to self-assemble into early embryo-like structures with an intestinal tract, the beginnings of a brain and a beating heart.
Since then, a race has been under way to translate this work into human models, and several teams have been able to replicate the very earliest stages of development.
The current research from the Cambridge-Caltech lab has not yet been fully described in a scholarly article. However, addressing at the conference, Ernicka-Goetz recounted growing the embryos to a level barely past the point at which a natural embryo would develop after 14 days.
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The model structures, which were each developed from a single embryonic stem cell, have begun to undergo gastrulation, a developmental stage in which the embryo changes from being a continuous sheet of cells to generating discrete cell lines and establishing the basic axis of the body, the Guardian reports, citing Ernicka-Goetz.
The model demonstrated the presence of primordial cells, which are the precursor cells of egg and sperm, although the embryo at this stage does not yet have a beating heart, a functioning gut, or the beginnings of a brain.
The development highlights how rapidly the science in this field has outpaced the law, and scientists in the UK and elsewhere are already moving to draw up voluntary guidelines to govern work on synthetic embryos. “If the whole intention is that these models are very much like normal embryos, then in a way they should be treated the same,” Lovell-Badge told the Guardian. “Currently in legislation they’re not. People are worried about this.”
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1 year ago