The past two years have been a rollercoaster ride of uncertainty, and just when the world thought the situation of Coronavirus pandemic was under control, a new variant, JN.1, has surfaced. This article aims to dissect the symptoms, causes, and implications of JN.1, the new strain of COVID-19. What is JN.1? How Does it Affect People? JN.1, an Omicron subvariant, surfaced in September last year amid declining temperatures, showing heightened transmission rates. Stemming from BA.2.86 (also known as Pirola), JN.1 possesses an additional spike protein mutation crucial for SARS-CoV-2 cell interaction.  The World Health Organization (WHO) categorises JN.1 as a Variant of Interest (VOI), distinct from its precursor BA.2.86, due to its rapid spread. Recently identified in the United States, close monitoring is essential to comprehend and address the dynamics of this evolving COVID-19 variant. The rise in JN.1 cases aligns with a general surge in COVID-19 infections. Symptoms of JN.1 infection closely resemble those of earlier Omicron variants, with no apparent increase in severity. While there are hints of potential increased diarrhoea cases, concrete data supporting this observation is currently lacking. Continuous monitoring is essential to better understand the characteristics of this variant.  Read more: Bangladesh reports 53 more Covid-19 cases in 24hrs Is JN.1 More Transmissible? JN.1, a descendant in the Omicron lineage, appears to be more transmissible than its precursor, BA.2.86. The observed surge in case numbers indicates increased transmissibility. Several newer variants, including JN.1, exhibit mutations affecting the spike protein's binding strength to respiratory cells, potentially enhancing replication and immune evasion.  While it remains early to precisely gauge JN.1's transmissibility and immune escape compared to other Omicron variants, experts assert its notable virulence. Dr. Joseph Khabbaza from the Cleveland Clinic notes that the current strain seems to deliver a more potent impact than its predecessors.  Who is at High Risk of Infection?  Certain groups face a higher risk of contracting the easily transmissible virus. These include: - People aged 65 and above- Diabetic people- People with neurological disorders- People who have pre-existing health conditions like COPD, heart diseases, chronic kidney diseases, cystic fibrosis, and individuals suffering from liver ailments- Pregnant women- Smokers- People with a compromised or weak immune system- Healthcare workers- People who are not vaccinated or have not taken booster shots. Read more: COVID-19: Bangladesh reports 35 more cases in 24hrs What are the Symptoms and Causes of the JN.1 COVID-19 Variant? JN.1's increasing prevalence implies heightened contagiousness or improved evasion of immune defences, as per the CDC. Currently, there is no evidence indicating it induces more severe disease than other strains, despite potential transmission spikes. Symptoms associated with JN.1 seem comparable to those induced by other strains, encompassing a range such as  - Sore throat- Congestion- Runny nose- Cough- Fatigue- Headache- Muscle aches- Fever or chills- Loss of sense of taste or smell- Shortness of breath or difficulty breathing- Nausea or vomiting- Diarrhoea The nature and intensity of symptoms typically rely more on an individual's overall health and immune condition rather than the specific variant causing the infection.  Read more: COVID-19: Bangladesh reports 28 more cases in 24hrs