The deceased were identified as Golam Mostafa, 45, of Godarpara in Sadar upazila and Rezaul Karim, 56, of Sirajganj.
Dr Farzanul Islam, health officer of Civil Surgeon office, said 45 people, including Shibganj Upazila Nirbahi Officer (UNO) Alamgir Kabir, have been infected with the virus in the last 24 hours.
The district has so far recorded 5,094 coronavirus cases.
Besides, the UNOs of Shonatala and Nandigram have been also diagnosed with the virus.
So far, 114 people have died of Covid-19 in the district.
Moreover, 3,833 people have recovered while 1,147 people are in isolation in the district.
Bangladesh’s confirmed Covid-19 cases have increased to 2,49,651 with the detection of 2,977 cases while 39 people died, bringing the death tally to 3,300 on Thursday.