Bangladesh reported 16 more Covid-19 cases in 24 hours till Sunday morning. With the new number, the country's total caseload rose to 2,037,532, according to the Directorate General of Health Services (DGHS). However, the official death toll from the disease remained unchanged at 29,442 as no new fatalities were reported. The daily case test positivity dropped to 0.45 percent from Saturday’s 0.46 percent as 3,531 samples were tested. Also read: Bangladesh logs 16 more Covid cases The mortality rate remained unchanged at 1.44 percent while the recovery rate rose to 97.79 percent. Bangladesh reported its highest daily caseload of 16,230 on July 28 in 2021 and daily fatalities of 264 on August 5 of the same year.  

The quickly changing coronavirus has spawned yet another super contagious omicron mutant that’s worrying scientists as it gains ground in India and pops up in numerous other countries, including the United States. Scientists say the variant – called BA.2.75 – may be able to spread rapidly and get around immunity from vaccines and previous infection. It’s unclear whether it could cause more serious disease than other omicron variants, including the globally prominent BA.5.      “It’s still really early on for us to draw too many conclusions,” said Matthew Binnicker, director of clinical virology at the Mayo Clinic in Rochester, Minnesota. “But it does look like, especially in India, the rates of transmission are showing kind of that exponential increase.” Whether it will outcompete BA.5, he said, is yet to be determined. Read: Covid-19 and economic crisis will end soon, hopes Hasan Mahmud Still, the fact that it has already been detected in many parts of the world even with lower levels of viral surveillance “is an early indication it is spreading,” said Shishi Luo, head of infectious diseases for Helix, a company that supplies viral sequencing information to the U.S. Centers for Disease Control and Prevention. The latest mutant has been spotted in several distant states in India, and appears to be spreading faster than other variants there, said Lipi Thukral, a scientist at the Council of Scientific and Industrial Research-Institute of Genomics and Integrative Biology in New Delhi. It’s also been detected in about 10 other countries, including Australia, Germany, the United Kingdom and Canada. Two cases were recently identified on the West Coast of the U.S., and Helix identified a third U.S. case last week. Fueling experts’ concerns are a large number of mutations separating this new variant from omicron predecessors. Some of those mutations are in areas that relate to the spike protein and could allow the virus to bind onto cells more efficiently, Binnicker said. Another concern is that the genetic tweaks may make it easier for the virus to skirt past antibodies — protective proteins made by the body in response to a vaccine or infection from an earlier variant. But experts say vaccines and boosters are still the best defense against severe COVID-19. In the fall it’s likely the U.S. will see updated formulations of the vaccine being developed that target more recent omicron strains. “Some may say, ‘Well, vaccination and boosting hasn’t prevented people from getting infected.’ And, yes, that is true,” he said. “But what we have seen is that the rates of people ending up in the hospital and dying have significantly decreased. As more people have been vaccinated, boosted or naturally infected, we are starting to see the background levels of immunity worldwide creep up.” It may take several weeks to get a sense of whether the latest omicron mutant may affect the trajectory of the pandemic. Meanwhile Dr. Gagandeep Kang, who studies viruses at India’s Christian Medical College in Vellore, said the growing concern over the variant underlines the need for more sustained efforts to track and trace viruses that combine genetic efforts with real world information about who is getting sick and how badly. “It is important that surveillance isn’t a start-stop strategy,” she said.

The coronavirus mutant that is now dominant in the United States is a member of the omicron family but scientists say it spreads faster than its omicron predecessors, is adept at escaping immunity and might possibly cause more serious disease. Why? Because it combines properties of both omicron and delta, the nation's dominant variant in the middle of last year. A genetic trait that harkens back to the pandemic's past, known as a “delta mutation," appears to allow the virus "to escape pre-existing immunity from vaccination and prior infection, especially if you were infected in the omicron wave," said Dr. Wesley Long, a pathologist at Houston Methodist in Texas. That's because the original omicron strain that swept the world didn’t have the mutation. The omicron “subvariant” gaining ground in the U.S. — known as BA.2.12.1 and responsible for 58% of U.S. COVID-19 cases last week — isn't the only one affected by the delta mutation. The genetic change is also present in the omicron relatives that together dominate in South Africa, known as BA.4 and BA.5. Those have exactly the same mutation as delta, while BA.2.12.1 has one that's nearly identical. Also read: WHO: COVID-19 cases mostly drop, except for the Americas This genetic change is bad news for people who caught the original omicron and thought that made them unlikely to get COVID-19 again soon. Although most people don't know for sure which variant caused their illness, the original omicron caused a giant wave of cases late last year and early this year. Long said lab data suggests a prior infection with the original omicron is not very protective against reinfection with the new mutants, though the true risk of being reinfected no matter the variant is unique to every person and situation. In a twist, however, those sickened by delta previously may have some extra armor to ward off the new mutants. A study released before it was reviewed by other scientists, by researchers at Ohio State University, found that COVID patients in intensive care with delta infections induced antibodies that were better at neutralizing the new mutants than patients who caught the original omicron. “The omicron infection antibody does not appear to protect well against the subvariants compared to delta,” said Dr. Shan-Lu Liu, a study author who co-directs the viruses and emerging pathogens program at Ohio State. But Liu said the level of protection a delta infection provides depends partly on how long ago someone was ill. That's because immunity wanes over time. People who got sick with delta shouldn’t think of themselves as invulnerable to the new subvariants, especially if they’re unvaccinated, Long said. “I wouldn’t say anyone is safe." Also read: Covid-19: Bangladesh reports 28 new cases, no death One bright spot? Booster shots can provide strong protection against the new mutants, Liu said. In general, vaccines and prior infection can protect people from the worst outcomes of COVID-19. At this point, scientists say, it's too early to know if the new mutant gaining ground in the U.S. will cause a significant uptick in new cases, hospitalizations and deaths. Scientists are still trying to figure out how virulent these new mutants are. Long said he hasn’t seen anything that answers that question for him, but Liu said emerging data points toward more serious illness. Liu said the subvariants have properties suggesting they spread more efficiently cell-to-cell. The virus "just hides in the cell and spreads through cell-to-cell contact,” Liu said. “That's more scary because the virus does not come out for the antibody to work.” Dr. Eric Topol, head of Scripps Research Translational Institute, said the new mutants certainly don’t appear less virulent than previous versions of omicron, and whether they are more virulent or not "will become clear in the months ahead.” In the meantime, scientists expect the latest powerhouse mutants to spread quickly, since they are more transmissible than their predecessors. Though home testing makes it tough to track all U.S. COVID cases, data from Johns Hopkins University shows that cases are averaging nearly 107,000 a day, up from about 87,000 two weeks ago. And new hospital admissions of patients with COVID-19 have been trending upwards since around mid-April, according to the Centers for Disease Control and Prevention. “I’m hopeful that we don’t see a similar increase in hospitalizations that we’ve had in prior waves,” Long said. “But with COVID, any time you have lots of people being infected, it’s just a numbers game. Some of those people are going to be severe. Some of those people are going to need hospitalization. Some of them, unfortunately, are going to pass away.”