Mizanur Rahman, superintendent of Sunamganj Police, said the victim, a student of Dirai Degree College and resident of Majlishpur, boarded on a Dirai-bound bus from Sylhet on Saturday night.
When the bus reached Sujanagar village around 9pm, the victim found that she was the only passenger.
At one stage, when the driver and helper of the bus tried to rape her she jumped off the bus and got injured.
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Later, she was taken to Sylhet Osmani Medical College Hospital.
The victim's father filed a case against the driver and helper of the bus at the night at Dirai Police Station.
Besides, the relatives of the victim demonstrated in front of the police station.
Meanwhile, Sunamganj Women Torture and Social Committee formed a human chain in front of Altaf Square around 11am on Sunday demanding arrest of the bus driver, its helper and contractor in this connection.
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The government has recently cleared the way for delivering highest punishment for rape.
The much-talked-about 'Women and Children Repression Prevention (Amendment) Bill, 2020' was passed in Parliament on November 17 for ensuring death penalty as the highest punishment for rape.
The government came up with the move after the rape incident at MC college and another in Noakhali fuelled countrywide protests against sexual violence against women.
Nearly a thousand rape incidents, including over 200 gang rapes, were reported between January and September this year, according to Ain o Salish Kendra (ASK).
Forty-five of the victims were killed after rape and 12 others took their own lives. Three women and nine men were killed for protesting against the incidents of sexual harassment, ASK said.