The number of people infected with a new virus in China tripled over the weekend, with the outbreak spreading from Wuhan to other major cities, reports BBC.
There are now more than 200 cases, mostly in Wuhan, though the respiratory illness has also been detected in Beijing, Shanghai and Shenzhen.
Three people have died. Japan, Thailand and South Korea have reported cases.
The new strain of coronavirus, which causes a type of pneumonia, can pass from person to person, China confirmed.
Respiratory expert Zhong Nanshan, who heads the health commission team investigating the virus, said 14 medical workers had caught it while treating patients, state media reported.
The sharp rise comes as millions of Chinese prepare to travel for the Lunar New Year holidays.
Although the outbreak is believed to have originated from a market, officials and scientists are yet to determine exactly how it has been spreading.
The outbreak has revived memories of the Sars virus - also a coronavirus - that killed 774 people in the early 2000s across dozens of countries, mostly in Asia. Analysis of the genetic code of the new virus shows it is more closely related to Sars than any other human coronavirus.
Experts in the UK told the BBC the number of people infected could still be far greater than official figures suggest, with estimates closer to 1,700.
What we know about the virus
2019-nCoV, as it's been labelled, is understood to be a new strain of coronavirus that has not previously been identified in humans
Coronaviruses are a broad family of viruses, but only six (the new one would make it seven) are known to infect people
Scientists believe an animal source is "the most likely primary source" but that some human-to-human transmission has occurred
Signs of infection include respiratory symptoms, fever, cough, shortness of breath and breathing difficulties
People are being advised to avoid "unprotected" contact with live animals, thoroughly cook meat and eggs, and avoid close contact with anyone with cold or flu-like symptoms
Source: World Health Organization
Who has been infected?
Authorities in Wuhan, a central Chinese city of 11 million that has been at the heart of the outbreak, on Monday said 136 new cases had been confirmed over the weekend, with a third person dying of the virus. There had previously been only 62 confirmed cases in the city.
As of late Sunday, officials said 170 people in Wuhan were still being treated in hospital, including nine in critical condition.
Beijing also confirmed its first cases, with five people infected. Shanghai confirmed its first case on Monday - a 56-year-old woman who came from Wuhan.
In the city of Shenzhen, a major tech hub close to Hong Kong, officials said a 66-year-old man showed symptoms of the virus following a trip to visit relatives in Wuhan.
State media reported 14 other cases in Guangdong province.
Four cases have been confirmed abroad - two in Thailand, one in Japan and one in South Korea - all of them involving people who are either from Wuhan or have visited the city.
In South Korea, the Korea Centers for Disease Control and Prevention said a 35-year-old Chinese woman was suffering from a fever and respiratory problems after travelling there from Wuhan. She was put into isolation and treated at a local hospital.
The World Health Organization said it was currently not recommending restrictions on travel or trade, but was providing guidance to countries preparing for any outbreak.
Airports in Singapore, Hong Kong and the Japanese capital Tokyo have been screening air passengers from Wuhan, and US authorities last week announced similar measures at three major airports in San Francisco, Los Angeles and New York.
What are the Chinese authorities saying?
How China is responding to the outbreak is under close scrutiny, given that it was widely criticised for initially covering up the Sars crisis in late 2002 and early 2003.
On Monday, Chinese President Xi Jinping for the first time publicly addressed the outbreak, saying that the virus must be "resolutely contained".
The foreign ministry, meanwhile, said China was providing "timely information about the disease" and would "work with all parties to deal with the virus".
China's National Health Commission on Monday confirmed that two cases in China were due to human-to-human transmission, state-run Xinhua news agency reported.
The commission had earlier said there had been no such cases, but that the virus had instead crossed the species barrier and come from infected animals at a seafood and wildlife market in Wuhan.
The WHO also said it believed there had been "some limited human-to-human transmission occurring between close contacts".
"As more… cases are identified and more analysis undertaken, we will get a clearer picture of disease severity and transmission patterns," it wrote on Twitter.
It noted that the rise in cases in China was a result of "increased searching and testing for [the virus] among people sick with respiratory illness".
What impact could Lunar New Year have?
From Friday, most Chinese will begin their week-long Lunar New Year holidays.
It's a time when hundreds of millions travel around China to visit family, raising fears that authorities will not be able to adequately monitor further spread of the disease.
Wuhan is a transport hub and authorities there have for nearly a week been using temperature scanners at airports, and train and bus stations. Those showing signs of fever have been registered, given masks and taken to hospitals and clinics.
Authorities say they will now also be screening everyone leaving the city.
At Beijing's central railway station, some travellers donned masks but did not appear overly concerned about the virus.
"Watching the news, I do feel a little worried. But I haven't taken precautionary measures beyond wearing regular masks," Li Yang, a 28-year-old account manager travelling to the region of Inner Mongolia, told the AFP news agency.
But the tone in Chinese social media, where the outbreak has been a top trending topic, was different.
"Who knows how many people who have been to Wuhan may be unaware that they have already been infected?" one Weibo user said.