The first of many freezer-packed COVID-19 vaccine vials made their way to distribution sites across the United States on Sunday, as the nation’s pandemic deaths approached new milestone of 300,000. The rollout of the Pfizer vaccine, the first to be approved by the Food and Drug Administration, ushers in the biggest vaccination effort in US history. Shots are expected to be given to health care workers and nursing home residents beginning Monday. Quick transport is key for the vaccine, especially since this one must be stored at extremely low temperatures — about 94 degrees below zero. Early Sunday, workers at Pfizer wasted no time as they packed vials into boxes. They scanned the packages and then placed them into freezer cases with dry ice. The vaccines were then taken from Pfizer’s Portage, Michigan, facility to Gerald R Ford International Airport in Grand Rapids, where the first cargo plane took off. Also read: US allows emergency COVID-19 vaccine in bid to end pandemic