Police could not immediately provide identities of the deceased.
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Locals said a Kushtia-bound bus overturned after colliding head-on with a truck in Barobazar area around 3pm. Ten people were killed on the spot and 30 more people were injured, police said.
Kaliganj Fire Service and Civil Defence station officer Mamunur Rashid said they recovered 10 bodies from the accident site.
Seven of the injured are in critical condition, he said, adding that the injured people had been sent to Kaliganj and Jashore hospitals.
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The accident halted vehicular movement on the Jashore-Jhenaidah road for a while.
Alarming rate of road crashes
At least 484 people were killed and 673 injured in 427 road accidents throughout the country in January this year.
Last month, the accident rates jumped by 25.58 percent and fatalities by 8.76 percent compared to the same period last year, according to Road Safety Foundation (RSF).
At least 445 lives were lost in 340 road accidents in January last year, according to RSF.
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Last month, 168 people were killed in 159 motorcycle accidents – 37.23 percent of total road accidents.
And 53 drivers and helpers were killed during the same period – 10.95 percent of total fatalities.